COVID-19 a complex multi-organ disease requires comprehensive diagnostic solutions

HUMAN supports laboratories with comprehensive solutions for the diagnosis of a wide range of aspects of COVID-19. For triage of SARS-CoV-2 patients, parameters of hematology and clinical chemistry are recommended. Coagulation parameters provide information on the prognosis of the patients.

Since the beginning of the COVID-19 pandemic, laboratories have been using nucleic acid amplification tests, such as RT-PCR. In many countries, access to this form of testing is still challenging. Therefore, rapid antigen tests are becoming increasingly important as they are close to the patient and relatively easy to use. HUMAN has found a reliable partner and manufacturer of SARS-CoV-2 antigen rapid tests and is now ready to provide you with these tests. To close the gap to molecular diagnostics, our partner Eiken Chemicals Co. was able to extend the existing product range of the LAMP solution to a SARS-CoV-2 Detection Kit - with the possibility to use saliva as sample.

In addition, the detection of antibodies in response to coronavirus infection is becoming increasingly important. Antibody detection is used, for example, to identify patients in later stages of infection or with previous infections, as well as for seroprevalence and epidemiological studies.
To meet the worldwide demand for specific and sensitive SARS CoV-2 antibody tests, HUMAN has signed a global distribution agreement with Beijing Wantai BioPharm, one of the leading manufacturers of diagnostics for infectious diseases.

Antigen Rapid Test - For the qualitative detection of SARS-CoV-2 antigen

In order to meet the increasing worldwide demand for antigen rapid tests and to be able to serve them flexibly, we have decided to distribute two antigen tests from our long-term partners.

Antigen tests like the colloidal gold RDT, are immunoassays that detect the presence of a specific viral antigen indicating a current viral infection. Antigen tests can be used at the point-of-care level.

SARS-CoV-2 Ag Rapid Test (saliva) 

REFLFA0401-25N
ProductColloidal gold immunoassay
Sensitivity/Specificity 95.51%/99.45% (saliva)
SampleNasopharyngeal and oropharyngeal swab specimens
Tests/kit25, incl. nasopharyngeal and oropharyngeal swabs, prefilled tubes
Storage2...30°C
ApprovalCE mark

SARS-CoV-2 Ag Rapid Test

REFWJ-2950
ProductColloidal gold immunoassay
Sensitivity / Specificity 96.10%/98.30%
SampleNasopharyngeal and oropharyngeal swab specimens
Tests/kit50, incl. nasopharyngeal swabs, tube & VTM
Storage2...30°C
ApprovalCE mark

You can place your order easily in our webshop at shop.human.de or request your personal offer at sales-covid@human.de.

Antibody Rapid Test - For the detection of antibodies of class IgM, IgG and IgA in one total Ab test

Wantai SARS-CoV-2 Ab Rapid Test for high sensitivity

REFWJ-2750
ProductRapid Test
Ig classTotal Ab = IgM + IgG + IgA
Labeling proteinS1-RBD (receptor binding domain)
Sensitivity / Specificity98,89%/94,7%
Sample10µl blood (venous, or capillary), serum, plasma
Tests/kit50, incl. buffer
ApprovalCE mark

Serological tests like the colloidal gold RDT, detect antibodies in the blood. They provide a positive result when an immune reaction to the pathogen has already taken place.

You can place your order easily in our webshop at shop.human.de or request your personal offer at sales-covid@human.de.

ELISA - For qualitative detection of total antibodies of class IgM, IgG and IgA to the SARS-CoV-2 virus

Wantai SARS-CoV-2 Ab ELISA

REFWS-1096
ProductELISA
Ig classTotal Ab = IgM + IgG + IgA
Labeling proteinS1-RBD (receptor binding domain)
Sensitivity / Specificity94.36%/100%
Sample100µl serum or plasma
Tests/kit96 x 1
ApprovalCE mark

The ELISA detects total antibodies (IgM, IgG and IgA) as indicative of an immune response to SARS-CoV-2 in patients suspected of previous SARS-CoV-2 infection, or for the detection of seroconversion in patients following known recent SARS-CoV-2 infection. The test may also be used to aid in the diagnosis of acute or past SARS-CoV-2 infection in conjunction with other tests and clinical information.

  • Specific detection of antibodies using the S1 domain of the spike protein including the immunologically relevant receptor binding domain (RBD)
  • RBD is an important target antigen for virus neutralizing antibodies
  • Fully automatic processing and result analysis with HUMAN ELISA instruments possible

"The first detectible serology marker with the highest sensitivity is total antibody"1 

1Lou B. et al. 2020 Serology characteristics of SARS-CoV-2 infection since the exposure and post symptoms onset 

SARS-CoV-2 LAMP test - For the molecular detection of SARS-CoV-2

The SARS-CoV-2 LAMP solution offers a lot of advantages as a molecular method. Besides a high sensitivity and specificity, the use of saliva as sample is possible. With a fast RNA extraction in less than 5 minutes and a simple operation results will be obtained in less than 60 minutes. Easy transport and storage of reagents as well as the possibility to perform the test in remote settings complete it.

LoopampTM SARS-CoV-2 Detection Kit

REFLMC403
ProductLoop-mediated isothermal amplification (LAMP)
SampleSaliva and nasopharyngeal or oropharyngeal swab specimens
Sensitivity/specificity90.0%/100.0%
Tests/kit48
Storage2...8°C
Shelf life12 months
ApprovalCE mark

LoopampTM Viral RNA Extraction Kit

REFLMC801
ProductRNA extraction
SampleSaliva and nasopharyngeal or oropharyngeal swab specimens
Tests/kit                  48
Storage2...8°C
Shelf life18 months
ApprovalCE mark

COVID-19 related diagnostic solutions

Genetic characteristics influence susceptibility to COVID-19 Blood group A a risk factor for COVID-19?

The rapid global spread of the noval SARS-CoV-2 virus is straining existing health resources, so identifying infected persons and prioritising people at high risk has become a critical challenge.

Publication about COVID-19 Kidney disease

An early warning for severity and complications
Several publications indicate that the novel coronavirus SARS-CoV-2 does not only affect the lungs but also impacts numerous other organs, like kidneys which have been observed to be the second most frequently affected organs.

Main laboratory abnormalities associated with COVID-19

Although RT-PCR is the recommended testing for diagnosis of a SARS-CoV-2 infection, there are numerous other diagnostic parameters that show abnormal laboratory results in COVID-19 patients. 

Supporting faster triage of COVID-19 patients by the use of hematology and CRP

In many countries, health organizations fear that they will find themselves in a situation where too many patients seek help in clinics, similar to the COVID 19 outbreak in Wuhan/China.

ISTH interim guidance on recognition and management of coagulopathy in COVID-19

According to recent observations, coagulopathy often occurs in severe cases of COVID-19 patients. Coagulopathy is a condition in which the ability of the blood to clot is impaired - a term that includes the thrombotic state in sepsis.

Hemostasis parameters as prognostic markers in COVID-19 patients

Is there a relationship between COVID-19 and hemostasis? A recent article by Lippi and Plebani provides an overview on the most frequent laboratory abnormalities encountered in patients with COVID-2019 infection.

Webinars on demand

SARS-CoV-2 antibody testing - the when, the what and the how

Learn about when antibody testing is most valuable, what you have to consider when choosing a test and how HUMAN provides solutions. Discuss the RDT and ELISA solutions provided by HUMAN with our experts.

Supporting faster triage of COVID-19 patients through the use of hematology and the role of blood groups in SARS-CoV-2 infection

Get an overview on strategies of fast decision makings on COVID-19 patients and learn about blood groups as a risk factor for a severe progress of the disease. Use the chance to exchange ideas with our product specialists in hematology and blood grouping.

Thromboinflammation in COVID-19: the importance of D-dimer and coagulation assays

Thrombotic and inflammatory events both contribute to acute organ damage in thromboinflammation, which is a  typical  characteristic of a severe course of COVID-19. 

Supporting faster triage of COVID-19 patients by the use of hematology and CRP

Learn more about the clinical and technical background also regarding COVID-19 for this very interesting win-win relationship and discuss with our specialists for hematology and COVID-19.

The importance of D-dimer and other Hemostasis parameters in COVID-19 patients

Learn more about the clinical background regarding the importance of D-dimer and other Hemostasis parameters

Publications

COVID-19 Publication List

This document contains a selection of relevant scientific publications related to COVID-19.The content has been compiled to the best of our knowledge and belief and makes no claim to completeness or correctness.

Interim Guidance on the Use of Rapid Antigen Tests for COVID-19 Response

This document provides guidance to Ministries of Health (MOHs), laboratorypersonnel and implementing partners in African Union Member States on theapplication of rapid antigen tests to COVID-19 testing.

Press Release

Distribution agreement on a global scale on serological tests to detect exposure to COVID-19

HUMAN Gesellschaft für Biochemica und Diagnostica mbH, signed a distribution agreement on a global scale for antibody related COVID-19 products. The...