COVID-19 a complex multi-organ disease requires comprehensive diagnostic solutions

HUMAN supports laboratories with comprehensive solutions for the diagnosis of a wide range of aspects of COVID-19. For triage of SARS-CoV-2 patients, parameters of hematology and clinical chemistry are recommended. Coagulation parameters provide information on the prognosis of the patients. 

Since the beginning of the COVID-19 pandemic, laboratories have been using nucleic acid amplification tests, such as RT-PCR. In many countries, access to this form of testing is still challenging. Therefore, rapid antigen tests are important as they are close to the patient and relatively easy to use. HUMAN has found reliable partners and manufacturers of SARS-CoV-2 antigen rapid tests and is now ready to provide you with these tests. To close the gap to molecular diagnostics, our partner Eiken Chemicals Co. was able to extend the existing product range of the LAMP solution to a SARS-CoV-2 Detection Kit - with the possibility to use saliva as sample. 

In addition, the detection of neutralizing antibodies in response to coronavirus infection is becoming increasingly important. Antibody detection is used, for example, as an indication of immunoprotection against infection in previously infected or vaccinated individuals. Along with a rapid test, HUMAN also offers a quantitative ELISA test that allows the determination of the corresponding neutralizing antibody titer. 

Antigen Rapid Test - For the qualitative detection of SARS-CoV-2 antigen

In order to meet the increasing worldwide demand for antigen rapid tests and to be able to serve them flexibly, we have decided to distribute two antigen tests from our long-term partners.

Antigen tests like the colloidal gold RDT, are immunoassays that detect the presence of a specific viral antigen indicating a current viral infection. Antigen tests can be used at the point-of-care level.

SARS-CoV-2 Ag Rapid Test (saliva) 

REFLFA0401-25N
ProductColloidal gold immunoassay
Sensitivity/Specificity 95.51%/99.45% (saliva)
SampleSaliva, anterior nasal, nasopharyngeal and oropharyngeal swab specimens
Tests/kit25, incl. swabs and tubes
Storage2...30°C
ApprovalCE mark

SARS-CoV-2 Ag Rapid Test

REFWJ-2950
ProductColloidal gold immunoassay
Sensitivity / Specificity 96.10%/98.30%
SampleNasopharyngeal and oropharyngeal swab specimens
Tests/kit50, incl. nasopharyngeal swabs, tube & VTM
Storage2...30°C
ApprovalCE mark

You can place your order easily in our webshop at shop.human.de or request your personal offer at sales-covid@human.de.

Neutralizing Antibody Rapid Test - For the detection of neutralizing antibodies to SARS-CoV-2

The presence of neutralizing antibodies to SARS-CoV-2 is the best current indication of immunoprotection against infection in previously infected or vaccinated individuals. The SARS-CoV-2 Neutralizing Antibody Rapid Test is a serological test to detect neutralizing antibodies to SARS-CoV-2. 

REFLFA0407-25N
ProductRapid Test
Labeling proteinS1-RBD (receptor binding domain)
Sensitivity / Specificity99,04%/95,45%
Sample10µl serum, plasma, whole blood and finger prick samples
Tests/kit25, incl. buffer, alcohol swabs, sterile lancets, micropipettes
ApprovalCE mark

Neutralizing Antibody ELISA - For quantitative detection of of neutralizing antibodies to SARS-CoV-2

REFWS-1596
ProductELISA
Labeling proteinS1-RBD (receptor binding domain)
Sensitivity / Specificity100%/99.6%
Sample100µl serum or plasma
Tests/kit96 x 1
ApprovalCE mark

The presence of neutralizing antibodies to SARS-CoV-2 is the best current indication of immunoprotection against infection in previously infected or vaccinated individuals. The SARS-CoV-2 Neutralizing Antibody ELISA is an Enzyme-linked immunosorbent assay for the quantitative detection of these neutralizing antibodies to SARS-CoV-2 virus. 

  • RBD is an important target antigen for virus neutralizing antibodies 
  • Fully automatic processing and result analysis with HUMAN ELISA instruments possible 
  • Use of single strips possible 

SARS-CoV-2 LAMP test - For the molecular detection of SARS-CoV-2

The SARS-CoV-2 LAMP solution offers a lot of advantages as a molecular method. Besides a high sensitivity and specificity, the use of saliva as sample is possible. With a fast RNA extraction in less than 5 minutes and a simple operation results will be obtained in less than 60 minutes. Easy transport and storage of reagents as well as the possibility to perform the test in remote settings complete it.

LoopampTM SARS-CoV-2 Detection Kit

REFLMC403
ProductLoop-mediated isothermal amplification (LAMP)
SampleSaliva and nasopharyngeal or oropharyngeal swab specimens
Sensitivity/specificity90.0%/100.0%
Tests/kit48
Storage2...8°C
Shelf life12 months
ApprovalCE mark

LoopampTM Viral RNA Extraction Kit

REFLMC801
ProductRNA extraction
SampleSaliva and nasopharyngeal or oropharyngeal swab specimens
Tests/kit                  48
Storage2...8°C
Shelf life18 months
ApprovalCE mark

COVID-19 related diagnostic solutions

Genetic characteristics influence susceptibility to COVID-19 Blood group A a risk factor for COVID-19?

The rapid global spread of the noval SARS-CoV-2 virus is straining existing health resources, so identifying infected persons and prioritising people at high risk has become a critical challenge.

Publication about COVID-19 Kidney disease

An early warning for severity and complications
Several publications indicate that the novel coronavirus SARS-CoV-2 does not only affect the lungs but also impacts numerous other organs, like kidneys which have been observed to be the second most frequently affected organs.

Main laboratory abnormalities associated with COVID-19

Although RT-PCR is the recommended testing for diagnosis of a SARS-CoV-2 infection, there are numerous other diagnostic parameters that show abnormal laboratory results in COVID-19 patients. 

Supporting faster triage of COVID-19 patients by the use of hematology and CRP

In many countries, health organizations fear that they will find themselves in a situation where too many patients seek help in clinics, similar to the COVID 19 outbreak in Wuhan/China.

ISTH interim guidance on recognition and management of coagulopathy in COVID-19

According to recent observations, coagulopathy often occurs in severe cases of COVID-19 patients. Coagulopathy is a condition in which the ability of the blood to clot is impaired - a term that includes the thrombotic state in sepsis.

Webinars on demand

Autoantibodies in COVID and Long-COVID - more cases of thrombosis and autoimmune disease on the horizon?

Since 2020 the corona virus keeps changing the world. But not only the mutations of the virus and the disease itself, but also lasting complications, such as long COVID are a topic of concern. As recent studies show, raised levels of autoantibodies, that are associated to COVID-19 can lead to the development of various autoimmune reactions and diseases. In this webinar we will have a spotlight on autoantibodies that specifically trigger platelet activation.

SARS-CoV-2 antibody testing - the when, the what and the how

Learn about when antibody testing is most valuable, what you have to consider when choosing a test and how HUMAN provides solutions. Discuss the RDT and ELISA solutions provided by HUMAN with our experts.

Supporting faster triage of COVID-19 patients through the use of hematology and the role of blood groups in SARS-CoV-2 infection

Get an overview on strategies of fast decision makings on COVID-19 patients and learn about blood groups as a risk factor for a severe progress of the disease. Use the chance to exchange ideas with our product specialists in hematology and blood grouping.

Thromboinflammation in COVID-19: the importance of D-dimer and coagulation assays

Thrombotic and inflammatory events both contribute to acute organ damage in thromboinflammation, which is a  typical  characteristic of a severe course of COVID-19. 

Supporting faster triage of COVID-19 patients by the use of hematology and CRP

Learn more about the clinical and technical background also regarding COVID-19 for this very interesting win-win relationship and discuss with our specialists for hematology and COVID-19.

The importance of D-dimer and other Hemostasis parameters in COVID-19 patients

Learn more about the clinical background regarding the importance of D-dimer and other Hemostasis parameters

Publications

COVID-19 Publication List

This document contains a selection of relevant scientific publications related to COVID-19.The content has been compiled to the best of our knowledge and belief and makes no claim to completeness or correctness.

Interim Guidance on the Use of Rapid Antigen Tests for COVID-19 Response

This document provides guidance to Ministries of Health (MOHs), laboratorypersonnel and implementing partners in African Union Member States on theapplication of rapid antigen tests to COVID-19 testing.

Press Release

Distribution agreement on a global scale on serological tests to detect exposure to COVID-19

HUMAN Gesellschaft für Biochemica und Diagnostica mbH, signed a distribution agreement on a global scale for antibody related COVID-19 products. The...