Malaria-LAMP for the detection of asymptomatic, sub-microscopic infections
During the amplification process, taking place at a constant temperature, 4 different primer pairs recognize 6 distinct regions of the target gene. The products obtained are a mixture of stem-loop DNA pieces with multiple loops (Loop-AMP). The detection of amplified products can be performed in two different ways, either by detection of calcein emitted fluorescence or by measuring the turbidity that is generated with the release of magnesium-pyrophosphate as a byproduct of target DNA amplification.
Easy-to-use LoopampTM technology for primary and peripheral laboratories
Especially designed as consolidated platform for sample preparation, amplification and easy visual result reading, HumaLoop M facilitates the sensitive and reliable detection for a variety of LoopampTM tropic pathogens assays, e.g. LoopampTMMalaria Panor LoopampTM Malaria Pan/Pf.
Scalable LoopampTM system for reference and regional laboratories
HumaTurb system allows for the real-time detection of turbidity based upon magnesium-pyrophosphate which is generated during the amplification process. The entire system consists of two parts, first HumaTurb C, for the setup and control of incubation time and temperature necessary for amplification of the LoopampTM assay reaction. The amplification takes place in the second part of the system, HumaTurb A.
- For small to medium throughput: up to 16 tests/run or up to 70 samples/day
- Preinstalled and fixed incubation times and temperatures for LoopampTM assays (except LoopampTM MTBC)
- Consolidated processing: sample preparation, amplification and detection on a single instrument
- Explicit interpretation by visual reading of fluorescence signals
- Results in 1 - 2 hrs