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Autoimmune DX
Endocrinology

Endocrinology

Autoimmune thyroid diseases (AITD) comprise two main clinical presentations:
Graves' disease (GD) and Hashimoto's thyroiditis (HT). Both are characterized by lymphocytic infiltration of the thyroid parenchyma. Both entities are regarded as organ specific and together constitute 30% of all cases of autoimmune diseases.

For the complete assessment of thyroid autoimmune diseases HUMAN provides ELISA assays for TSH and thyorid hormones (fT3 and fT4).

ELISA - Detection of thyroid autoantibodies (anti-TPO, anti-TG and anti-TR antibodies)

TG-Antibodies

Quantitative determination of IgG antibodies to thyroglobulin.

Calibration: 15 / 60 / 240 / 960 / 3840 IU/ml

Cut-off: 80-200 IU/ml

Antigens	REF	Size
Thyroglobulin	ITC85010	96

TPO-Antibodies

Quantitative determination of IgG antibodies to thyroperoxidase.

Calibration: 11.5 / 46 / 183 / 732 / 2930 IU/ml

Cut-off: 80-150 IU/ml

Antigens	REF	Size
Thyroperoxidase	ITC85020	96

TSH Receptor Antibodies

Quantitative determination of IgG antibodies to TSH-receptor.

Calibration: 1 / 2 / 8 / 40 U/ml

Cut-off: 1.1-1.5 U/ml

Antigens	REF	Size
TSH-receptor	ITC85030	96

ELISA - Detection of thyroid hormones

fT3 (Free Triiodothyronine)

Quantitative determination of free Triiodothyronine.

Calibration: 0 / 1 / 3 / 5 / 8 / 16 pg/ml

Antigens	REF	Size
T3	54015	96

fT4 (Free Thyroxine)

Quantitative determination of free Thyroxine.

Calibration: 0 / 0.40 / 1.25 / 2.10 / 5.00 / 7.40 ng/dl

Antigens	REF	Size
T4	54025	96

TSH (Thyrotropin)

Quantitative determination of Thyrotropin.

Calibration: 0 / 0.5 / 3 / 6 / 15 / 30 mlU/l

Antigens	REF	Size
TSH	54030	96