Roche cobas c 111 or HumaStar 100: Which Clinical Chemistry Analyzer To Choose

Explore the features and specifications of the HumaStar 100 and Roche cobas c 111 clinical chemistry analyzers to determine which one best fits your laboratory's needs.

Company HUMAN Roche
Model HumaStar 100 cobas c 111
Throughput max. tests/h 100 65 tests/hour for photometry tests only
180 tests/hour for ISE tests only
Up to 100 tests/hour for mixed requests
Reagent positions 30 27
Reagent cooling independent from main power switch -
Sample positions 60 8
Sample barcode reader Internal -
Cuvettes 80 reusable -
Water consumption (l/h) < 1 (8 ml/test) 2.5 - 3 l/d

*All information is correct as of December 2023



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Selecting the appropriate clinical chemistry analyzer is vital for laboratories aiming to enhance testing efficiency, accuracy, and reliability. In this comprehensive comparison, we'll analyze the features and specifications of two prominent analyzers: the HumaStar 100 and Roche cobas c 111, to assist you in choosing the best option for your laboratory's needs.


Efficient throughput is crucial for laboratories processing a high volume of tests, ensuring prompt results and optimized workflow.

  • HumaStar 100: Offers a maximum throughput of 100 tests per hour, suitable for laboratories with moderate testing volumes.
  • Roche cobas c 111: Provides a throughput of 65 tests per hour for photometry tests only, 180 tests per hour for ISE tests only, and up to 100 tests per hour for mixed requests, catering to various laboratory requirements.

Reagent Positions

The number of reagent positions determines the analyzer's flexibility in conducting different tests without frequent reagent changes.

  • HumaStar 100: Features 30 reagent positions, allowing for a diverse range of tests with stable reagent conditions.
  • Roche cobas c 111: Offers 27 reagent positions, ensuring versatility in conducting tests while maintaining stable reagent conditions.

Reagent Cooling

Maintaining stable reagent temperatures is crucial for accurate and reliable test results, especially in demanding laboratory environments.

  • HumaStar 100: Ensures reagent stability with independent cooling from the main power switch, preserving reagent integrity throughout testing.
  • Roche cobas c 111: Information not available.

Sample Positions

Adequate sample positions are essential for managing varying sample volumes efficiently, addressing the laboratory's diverse testing needs.

  • HumaStar 100: Offers 60 sample positions, accommodating laboratories with diverse sample processing requirements.
  • Roche cobas c 111: Provides 8 sample positions, suitable for laboratories with lower sample volumes and optimizing sample management.

Sample Barcode Reader

Integration of an internal sample barcode reader enhances testing accuracy and traceability, ensuring seamless sample identification and result linkage.

  • HumaStar 100: Incorporates an internal sample barcode reader, improving testing process integrity and minimizing errors.
  • Roche cobas c 111: Information not available.


The type and capacity of cuvettes impact operational costs and environmental sustainability, influencing the analyzer's overall cost-effectiveness.

  • HumaStar 100: Utilizes 80 reusable cuvettes, promoting sustainable laboratory practices and minimizing waste, contributing to cost efficiency.
  • Roche cobas c 111: Information not available.

Water Consumption

Monitoring water consumption is crucial for sustainable laboratory management, reducing operational costs and environmental impact.

  • HumaStar 100: Consumes less than 1 liter of water per hour (8 ml/test), contributing to cost efficiency and environmental sustainability.
  • Roche cobas c 111: Utilizes 2.5 to 3 liters of water per day, ensuring efficient cooling and optimal instrument performance.


Both the HumaStar 100 and Roche cobas c 111 offer advanced features and reliable performance tailored to meet the evolving needs of modern laboratories. The choice between the two depends on your laboratory's specific requirements, such as testing volume, flexibility, and operational preferences. Consider factors such as throughput, reagent and sample positions, water consumption, and sample barcode reader integration to make the best decision aligned with your laboratory's goals and priorities.