Bio-Rad Evolis or Elisys Quattro: Which ELISA Analyzer To Choose?

Automated ELISA analyzers such as the Elisys Quattro and Bio-Rad Evolis offer a range of features and specifications to help you determine the best fit for your laboratory's needs.

Company Elisys Quattro Bio-Rad
Model Elisys Quattro Evolis
Analyzer type 4-plate fully automated ELISA analyzer 4 plates automation solution of microplate-based ELISA analysis
Plate loading capacity Up to 7 plates/run 4 plates
Samples positions Up to 180 tubes On-board capacity for up to 180 samples
Reagent positions 60 positions on five reagent racks 31 Calibrator & Control capacity
Internal barcode reader Sample ID, rack type Automatic barcode scanning
Pipetting system 300 μl and 1100 μl carbon tips (conductive) Tips in 300 μL or 1100 μL volumes
Number of tips Up to 5 tip racks for 300 μI, or 1100 μI disposable tips Held in racks of 96 tips, Disposable tips eliminate carryover contamination
Onboard capacity tips 480 tips Station holds 480 tips in 5 racks
Computer External External
Interfaces R232 RS-232 Serial Port, ASTM or ASCII format
LIS bi-directional, ASTM & free definable protocol Bi-directional interface to exchange information with LIS, Ability to link multiple units to a single LIS interface

*All information is correct as of March 2024


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Selecting the right automated ELISA analyzer can significantly impact laboratory efficiency and testing accuracy. This article delves into the functionalities and features of the Biorad Evolis and Elisys Quattro, helping you make an informed decision.

Analyzer Type

This defines how the analyzer operates, impacting its suitability for specific laboratory workflows.

  • Elisys Quattro: Offers a 4-plate fully automated system designed for efficiency in medium to high-throughput settings.
  • Bio-Rad Evolis: Provides a 4-plate automation system focused on microplate-based ELISA analysis, suitable for labs that require precise, streamlined operations.

Plate Loading Capacity

Determines how many tests can be processed in a single batch, directly affecting throughput capabilities.

  • Elisys Quattro: Can manage up to 7 plates per run, which is beneficial for labs looking to maximize test volume without frequent reloads.
  • Bio-Rad Evolis: Handles up to 4 plates per run, ideal for smaller or more specialized testing environments.

Samples Positions

The number of samples the system can hold, which influences the testing volume and operational efficiency.

  • Elisys Quattro: Supports up to 180 tubes, allowing for extensive simultaneous testing, reducing turnaround time.
  • Bio-Rad Evolis: Equally capable of holding up to 180 samples, optimized for efficient sample handling in various lab setups.

Reagent Positions

Reflects the capacity for storing multiple reagents, which is crucial for labs that perform a variety of tests.

  • Elisys Quattro: Provides 60 positions across five racks, offering versatility and reducing the need for frequent reagent swaps.
  • Bio-Rad Evolis: Has 31 calibrator and control positions, which may limit test diversity but simplifies operations for focused test menus.

Internal Barcode Reader

Enhances the automation process by accurately identifying samples and reagents, reducing manual data entry errors.

  • Elisys Quattro: Capable of identifying sample ID and rack type, streamlining the sample handling process.
  • Bio-Rad Evolis: Features advanced barcode scanning capabilities for all conventional types, enhancing data accuracy and laboratory efficiency.

Pipetting System

Critical for accurate liquid handling, directly affecting test accuracy and reproducibility.

  • Elisys Quattro: Uses conductive carbon tips for precise pipetting, suitable for labs requiring high precision in sample preparation.
  • Bio-Rad Evolis: Also utilizes conductive tips, ensuring high accuracy and consistency in test results.

Number of Tips

Affects the continuity and efficiency of operations by determining how long the system can operate before needing maintenance.

  • Elisys Quattro: Can use up to 5 racks of tips, supporting extended operation without interruptions for tip replacement.
  • Bio-Rad Evolis: Features racks that hold 96 disposable tips each, minimizing contamination and supporting efficient operations.

Onboard Capacity for Tips

Indicates the maximum number of tips the machine can store, impacting the duration of continuous use.

  • Elisys Quattro: Stores up to 480 tips, facilitating long periods of uninterrupted testing.
  • Bio-Rad Evolis: Matches this capacity, with a similar design to support sustained operational efficiency.

Computer and Interfaces

These systems control the analyzer and manage data flow, essential for integration with laboratory workflows.

  • Both analyzers: Use external computers for operation. The Quattro uses an RS232 interface, while the Evolis offers an RS-232 serial port and supports ASTM or ASCII formats, providing flexible data integration options.

Laboratory Information System (LIS)

The system’s compatibility with information management systems, crucial for integrating test data into broader laboratory operations.

  • Elisys Quattro: Supports bi-directional communication and a variety of protocols, enhancing its adaptability to different lab environments.
  • Bio-Rad Evolis: Offers bi-directional interfaces and the capability to link multiple units to a single LIS, making it ideal for expanding laboratories looking to scale operations efficiently.


Both the Bio-Rad Evolis and Elisys Quattro bring robust capabilities to the table, each with features that cater to different laboratory needs. The choice between them should be guided by the specific demands of your testing volume, operational workflow, and integration requirements. Consider the Elisys Quattro for its higher throughput and versatile reagent handling if your lab processes a large volume of tests routinely. On the other hand, the Bio-Rad Evolis may be more suited for labs that prioritize precision and scalability, especially those planning to expand operations or integrate multiple analyzers into a cohesive network. Evaluate both options in the context of your lab's current and future needs to select the best automated ELISA analyzer.