Beckman Coulter Access 2 or HumaCLIA 150: Which Immunoassay Analyzer To Choose?

Chemiluminescence immunoassay (CLIA) analyzers such as the HumaCLIA 150 and Access 2 offer advanced features and capabilities to meet the diverse needs of today's diagnostic laboratories. Understanding the specific benefits of each model can help you select the optimal instrument for your laboratory's needs.


Company HUMAN Beckman Coulter
Model HumaCLIA 150 Access 2
Type of Instrument Benchtop Benchtop
Mode Continuous access Continuous access
Detection based on Acridinium ester (AE) Alkaline phosphatase (ALP)
Throughput (up to) 150 t/h 100 t/h
Assay time approx. 30 min 30 to 75 min
Reagent positions 20 refrigerated 24 refrigerated
Sample positions 50 60
STAT positions (Emergency samples) 50 Yes
Reaction cuvettes onboard capacity 1000 cuvettes Yes
Cuvette format Single cuvettes in bulk format Cuvettes

*All information is correct as of March 2024



Selecting the right immunoassay analyzer can significantly enhance laboratory efficiency and accuracy. This comparison between the HUMAN HumaCLIA 150 and Beckman Coulter Access 2 highlights their key features to help you decide which one best meets your laboratory needs.

Detection based on

The detection method used in immunoassay analyzers significantly affects the sensitivity and specificity of the tests, impacting the accuracy and reliability of results.

  • HumaCLIA 150: Utilizes Acridinium ester (AE), a chemiluminescent substrate known for its high sensitivity and specificity, making it suitable for a wide range of assays.
  • Access 2: Uses Alkaline phosphatase (ALP), which is effective for various tests but may not offer the same level of sensitivity as AE.

Throughput (up to)

Throughput capacity is crucial for laboratories with high sample volumes, as it determines the number of tests processed per hour, impacting overall efficiency and productivity.

  • HumaCLIA 150: Offers a maximum throughput of 150 tests per hour, ideal for high-volume testing environments.
  • Access 2: Provides a throughput of 100 tests per hour, which may be suitable for medium-volume laboratories.

Assay time

Assay time influences the speed at which individual tests are completed, affecting the turnaround time for results and overall laboratory workflow.

  • HumaCLIA 150: Has an approximate assay time of 30 minutes, providing a balance between rapid processing and detailed analysis.
  • Access 2: Features an assay time ranging from 30 to 75 minutes, offering flexibility but potentially slower turnaround for some tests.

Reagent positions

The number of reagent positions is critical for laboratories conducting diverse tests, as it determines how many different assays can be run without frequent reagent changes.

  • HumaCLIA 150: Equipped with 20 refrigerated reagent positions, supporting a wide range of tests and minimizing reagent change frequency.
  • Access 2: Offers 24 refrigerated reagent positions, providing slightly more capacity for various assays.

Sample positions

Adequate sample positions are essential for managing sample volumes effectively, preventing backlogs, and ensuring smooth laboratory operations.

  • HumaCLIA 150: Provides 50 sample positions, catering to higher sample volumes and including provisions for urgent STAT samples.
  • Access 2: Offers 60 sample positions, accommodating larger sample volumes and enhancing operational efficiency.

STAT positions (Emergency samples)

Efficient handling of STAT (emergency) samples is vital for clinical laboratories, ensuring priority processing without disrupting routine workflows.

  • HumaCLIA 150: Integrates STAT sample handling within its 50 sample positions, allowing for seamless inclusion of urgent tests.
  • Access 2: Includes dedicated STAT sample handling capabilities, ensuring prompt processing of emergency samples.

Reaction cuvettes onboard capacity

Onboard cuvette capacity determines how many reactions can be run before needing to reload, impacting efficiency and continuous operation.

  • HumaCLIA 150: Has a capacity of 1000 cuvettes, supporting high-throughput operations.
  • Access 2: Provides onboard capacity, although the exact number is unspecified, ensuring sufficient cuvettes for continuous workflow.

Cuvette format

The format of cuvettes affects handling and loading efficiency in the analyzer.

  • HumaCLIA 150: Uses single cuvettes in bulk format, facilitating easy loading and handling.
  • Access 2: Utilizes cuvettes, designed for streamlined operation within the system.

Type of Instrument

The type of instrument influences the space requirements and overall suitability for different laboratory setups. Both the HumaCLIA 150 and Access 2 are benchtop analyzers, making them suitable for laboratories with limited space while providing high-performance capabilities.

  • HumaCLIA 150: A compact benchtop analyzer ideal for high-volume testing environments.
  • Access 2: Another benchtop analyzer suitable for medium-volume laboratories needing a versatile instrument.


The operational mode affects how samples and reagents are processed during the testing workflow. Both the HumaCLIA 150 and Access 2 operate in continuous access mode, ensuring consistent processing capability and accommodating varying sample volumes seamlessly.

  • HumaCLIA 150: Allows for uninterrupted sample and reagent addition, enhancing workflow efficiency.
  • Access 2: Provides consistent processing capability, accommodating varying sample volumes seamlessly.

Reaction cuvettes onboard capacity

Onboard cuvette capacity is essential for ensuring the analyzer can handle a high number of reactions without frequent interruptions for reloading, thus supporting continuous and efficient workflow.

  • HumaCLIA 150: Features an onboard capacity of 1000 cuvettes, making it suitable for high-throughput environments where continuous operation is crucial.
  • Access 2: While the exact number of onboard cuvettes is not specified, it supports sufficient capacity for continuous workflow in medium-volume labs.

Cuvette format

The format of the cuvettes impacts ease of handling and loading efficiency. This feature is vital for maintaining smooth operations and reducing the time needed for manual interventions.

  • HumaCLIA 150: Uses single cuvettes in bulk format, which facilitates easy handling and loading, contributing to efficient laboratory workflow.
  • Access 2: Utilizes cuvettes designed for streamlined operation within the system, ensuring ease of use and maintaining operational efficiency.


The choice between the HumaCLIA 150 and Access 2 should be based on the specific priorities and requirements of your laboratory. Considerations include testing volume, reagent and sample capacity, STAT sample handling, assay time, and cuvette management. By evaluating these factors, laboratories can make a well-informed decision that aligns with their operational needs and testing demands.


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