Abbott ARCHITECT i1000SR or HumaCLIA 150: Which Immunoassay Analyzer To Choose?

Chemiluminescence immunoassay (CLIA) analyzers such as the HumaCLIA 150 and Abbott ARCHITECT i1000SR offer advanced features and capabilities to meet the diverse needs of today's diagnostic laboratories. Understanding the specific benefits of each model can help you select the optimal instrument for your laboratory's needs.


Company HUMAN Abbott
Model HumaCLIA 150 ARCHITECT i1000SR
Type of Instrument Benchtop Floor-standing
Mode Continuous access Continuous access
Detection based on Acridinium ester (AE) Acridinium ester (AE)
Throughput (up to) 150 t/h 100 t/h
Assay time approx. 30 min 29 up to 43 min
Reagent positions 20 refrigerated 25 refrigerated
Sample positions 50 65
STAT positions (Emergency samples) 50 35
Reaction cuvettes onboard capacity 1000 cuvettes yes
Cuvette format Single cuvettes in bulk format Single cuvettes in bulk format

*All information is correct as of March 2024



Selecting the right immunoassay analyzer can significantly enhance laboratory efficiency and accuracy. This comparison between the HUMAN HumaCLIA 150 and Abbott ARCHITECT i1000SR highlights their key features to help you decide which one best meets your laboratory needs.

Instrument Type and Mode

The type and mode of the instrument are fundamental in determining its suitability for different laboratory environments and workflows.

HumaCLIA 150: This model is a benchtop analyzer with continuous access mode, allowing for efficient handling of samples and reagents without workflow interruption.

ARCHITECT i1000SR: Differing from the HumaCLIA 150, this is a floor-standing analyzer with continuous access mode, catering to laboratories with higher space availability and potentially larger sample volumes.

Detection Methods

The detection method is a crucial factor in determining the analyzer's sensitivity and specificity, directly impacting the accuracy of test results.

HumaCLIA 150: Utilizes Acridinium Ester (AE) for detection, a chemiluminescent substrate known for its high sensitivity and specificity.

ARCHITECT i1000SR: Also uses Acridinium Ester (AE) for detection, ensuring high sensitivity and specificity in test results, similar to the HumaCLIA 150.

Throughput and Assay Time

Throughput is essential for laboratories that handle high sample volumes, determining how many tests can be processed within a given timeframe. Assay time affects the speed at which individual tests are completed.

HumaCLIA 150: Offers a maximum throughput of 150 tests per hour, making it suitable for high-volume testing environments. The assay time is approximately 30 minutes.

ARCHITECT i1000SR: Has a throughput of 100 tests per hour, with an assay time ranging from 29 to 43 minutes, balancing speed and comprehensive analysis.

Reagent Positions

The number of reagent positions influences the analyzer's flexibility in conducting various tests and the frequency of reagent changes required.

HumaCLIA 150: Equipped with 20 refrigerated reagent positions, supporting a wide range of tests and reducing the need for frequent reagent replacement.

ARCHITECT i1000SR: Offers the most with 25 refrigerated reagent positions, allowing for extensive testing without frequent reagent changes.

Sample Positioning

Adequate sample positions are crucial for managing sample volumes effectively, preventing backlogs, and maintaining smooth laboratory operations.

HumaCLIA 150: Provides 50 sample positions, suitable for higher sample volumes and including provisions for urgent STAT samples.

ARCHITECT i1000SR: Features 65 sample positions, accommodating larger sample volumes efficiently.

STAT Sample Handling

Handling STAT (emergency) samples efficiently is vital for clinical laboratories, ensuring priority processing without disrupting routine workflows.

HumaCLIA 150: Integrates STAT sample handling within its 50 sample positions, allowing for seamless inclusion of urgent tests in the workflow.

ARCHITECT i1000SR: Provides 35 STAT sample positions, balancing routine and emergency sample processing effectively.

Reaction Cuvettes Onboard Capacity

The onboard capacity of reaction cuvettes affects how long the analyzer can operate without needing cuvette replacement, impacting efficiency and workflow continuity.

HumaCLIA 150: Boasts a substantial onboard capacity of 1000 reaction cuvettes, supporting extended continuous operation and reducing the frequency of interruptions for cuvette replacement.

ARCHITECT i1000SR: Indicates the availability of reaction cuvettes without specifying a precise onboard capacity, implying sufficient capacity for continuous operations.

Cuvette Format

The format of cuvettes can influence the ease of use, operational efficiency, and cost-effectiveness of the analyzer.

HumaCLIA 150: Uses single cuvettes in bulk format, advantageous for high-volume testing environments due to easier handling and lower costs.

ARCHITECT i1000SR: Similar to the HumaCLIA 150, it uses single cuvettes in bulk format, providing efficient handling and cost management.


The choice between the HumaCLIA 150 and ARCHITECT i1000SR should be based on the specific priorities and requirements of your laboratory. Considerations include testing volume, reagent and sample capacity, STAT sample handling, and cuvette management. By evaluating these factors, laboratories can make a well-informed decision that aligns with their operational needs and testing demands.


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